Relevant Publications

Zeringue, H. C., M. B. Wheeler and D. J. Beebe, "A Microfluidic Method for Removal of the Zona Pellucida from Mammalian Embryos," Lab on a Chip, vol. 5, pp. 108-110, 2005.

Zeringue, H. C., J. J. Rutledge and D. J. Beebe, "Early Mammalian Embryo Development Depends on Cumulus Removal Technique," Lab on a Chip, vol. 5, pp. 86-90, 2005.

Clark, S. G., E. M. Walters, D. J. Beebe and M. B. Wheeler, "In Vitro Fertilization in Microfluidic Channels Enhances Monospermic Penetration of Swine Oocytes," Reprod Fertil Dev, vol. 16, pp. 239, 2004.

Wheeler, M. B., S. G. Clark and D. J. Beebe, "Developments in In Vitro technologies for swine embryo production," Reproduction, Fertility and Development, vol. 16, pp. 15-25, 2004.

Zeringue, H. C. and D. J. Beebe, "Microfluidic Removal of Cumulus Cells from Mammalian Zygotes," Methods in Molecular Biology, vol. 254: Germ Cell Protocols, Volume 2: Molecular Embryo Analysis, Live Imaging, Transgenesis, and Cloning, H. Schatten, Ed. Totowa, NJ: Humana Press, 2003, pp. 365-373.

Walters, E. M., S.G. Clark, D.J. Beebe and M.B. Wheeler, "Mammalian Embryo Culture in a Microfluidic Device," Methods in Molecular Biology, vol. 254: Germ Cell Protocols Volume II: Molecular Embryo Analysis, Live Imaging, Transgenesis, and Cloning. Ed. Heidi Schatten, Humana Press, 2003, pp. 375-382.

Clark, S. G., E. M. Walters, D. J. Beebe and M. B. Wheeler, "Determination of the BSA content needed for culture of porcine embryos fertilized in microchannels," Biology of Reproduction, vol. 68, pp. 336, 2003.

Beebe,D.J., M. B. Wheeler, H. Zeringue, E.M. Walters and S Raty, " Microfluidic technology for assisted reproduction," Theriogenology , Vol. 57, No. 1, pp.125-136, 2002.

Hester P.N., H.M. Roseman, S.G. Clark, E.M. Walters, D.J. Beebe, M.B. Wheeler, " Enhanced Cleavage Rates Following In Vitro Maturation of Pig Oocytes Within Polydimethylsiloxane-Borosilcate Microchannels," Theriogenology, Vol. 57, No. 1, p.723, 2002.

Zeringue H., E.M. Walters, L.L. Leibfried-Rutledge, M.B. Wheeler, D.J. Beebe, "Development of Bovine In Vitro Produced Embryos after Cumulus Cell Removal with a Microfluidic Microchannel Device," Theriogenology , Vol. 57, No. 1, p533, 2002.

Zeringue, H., M. B. Wheeler and D. J. Beebe, "Removal of cumulus from mammalian oocytes using microfluidic techniques," Biomedical Microdevices, Vol. 3, pp. 219-224, 2001.

Glasgow, I., H. C. Zeringue, D. J. Beebe, Seong-Jun Choi, J. Lyman, Natalie G. Chan and M. Wheeler, "Handling individual mammalian embryos using microfluidics," IEEE Trans. Biomed. Eng, Vol. 48, No. 5, pp. 570-578, 2001.

Walters, E.M., D.J. Beebe, M.B. Wheeler, "In Vitro Maturation of Pig Oocytes in PDMS and Silicon Microfludic Devices," Theriogenology, Vol.55, No. 1, p.497, 2001.

Raty, S., J.A. Davis, D.J. Beebe, S.L. Rodriguez-Zas, and M.B. Wheeler, "Culture in microchannels enhances in vitro embryonic development of preimplantation mouse embryos," Theriogenology, Vol. 55, No.1, p.241, 2001.

Clark, S.G., J. Davis, D. J. Beebe, M.B. Wheeler, "Biocompatibility of Porcine Sperm Cells in Polydimethylsiloxane (PDMS)," Theriogenology Vol. 55, No.1, p.421, 2001.

Beebe, D. J., "Microfluidic systems for assisted reproduction," Lab Automation, January 27-30, 2001, Palm Springs, California.

Davis, J. A., S. Raty, D. T. Eddington, M.B. Wheeler, I. K. Glasgow and D. J. Beebe, "Development of Microfluidic Systems for the Culture of Mammalian Embryos," First International IEEE EMBS Special Topic Conference on Microtechnology in Medicine and Biology, October 12-14, 2000, Lyon, France.

Zeringue, H., I. Glasgow, S. Raty, K. King, M. Wheeler and D. J. Beebe, "Embryo manipulation and zona pellucida removal in a polydimethylsiloxane microfluidic system," World Congress on Medical Physics and Biomedical Engineering, Chicago, July 23-38, 2000.

Zeringue, H. C., M. B. Wheeler and D. J. Beebe, "Removal of cumulus cells from mammalian oocytes in a microfluidic system," Solid-State Sensor and Actuator Workshop, June 4-8, Hilton Head, S.C., 2000.

Zeringue, H. C., K. R. King, I. K. Glasgow, S. Raty, M. B. Wheeler and D. J. Beebe, "Zona pellucida removal of mammalian embryos in a microfluidic system," µTAS 2000, May 14-18, The Netherlands.

Zeringue, H. C., I. K. Glasgow, D. J. Beebe, J. T. Lyman, and M. B. Wheeler, "Micro fluidic single embryo culture systems in PDMS," presented at 21st Ann. Int'l. Conf. of the IEEE Eng. in Med. and Bio. Soc. and the 1999 Ann. Fall Meeting of the Biomed. Eng. Society, Atlanta, GA, Oct. 13-16, 1999.

Chan, N.G., J.T. Lyman, S. J. Choi, H.C. Zeringue, I.K. Glasgow, D.J. Beebe, and M.B. Wheeler, "Development of an embryo transport and analysis system: material biocompatability," Theriogenology Vol. 51, No.1, p.234, 1999.

Glasgow, I. K., H. C. Zeringue, D. J. Beebe, Seong-Jun Choi, J. Lyman, and M. Wheeler, "Individual embryo transport on a chip for a total analysis system," Third Conference on Micro Total Analysis Systems, Banff, CA, October 13-16, 1998.

Zeringue, H. C., I. K. Glasgow, D. J. Beebe, S. J. Choi, J. T. Lyman, M.B.Wheeler, "Impedance-based detection of individual embryos, " Biomedical Engineering Society Annual Meeting, Cleveland, OH, October 10-13, 1998.

Choi, S-J., I. Glasgow, H. Zeringue, D. J. Beebe and M. B. Wheeler. "Development of Microelectromechanical Systems to Analyze Individual Mammalian Embryos: Embryo Biocompatability." Biol Reprod. (Suppl.1), Society for the Study of Reproduction, 1998.

Wang, L., D. J. Beebe, A. R. Williams and K. Easley, "Electrothermal branding for embryo labeling," IEEE Trans. Biomed. Eng, Vol. 44, No. 11, pp. 1128-1138, 1997.

K. D. Easley, A. R. Williams, D. J. Beebe, L. Wang, "Micro-labeling of bovine embryos: polysilicon micro-chip biocompatibility, J. Animal. Sci., vol. 75 (suppl. 1), pp. 18, 1997.

Wang, L., D. J. Beebe, A. Williams and K. Easley, "The application of surface micromachining to embryo labeling," Late News Paper, Solid-State and Actutator Workshop, Hilton Head, SC, June 2-6, 1996.

Wang, L., D. J. Beebe, A. Williams and K. Easley, "Electrothermal branding of bovine embryos," Proc. 18th Annu. Int. Conf. IEEE Eng. Med. Biol. Soc., Amsterdam, The Netherlands, October 31-November 2, 1996.